Swine respiratory disease

Swine respiratory disease

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This book aims at providing an updated overview on the most frequent pathogens responsible for Porcine Respiratory Disease Complex (PRDC), viruses and bacteria, acting in association and mainly potentiating their anatomical and functional effects and worsening the clinical outcome and economic impact.

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The authors, prestigious and rewarded experts with a wide experience in respiratory diseases in pigs, have focused their efforts on preparing chapters that illustrate the latest information and data on the treated topics, while making them as readable as possible. The book inspires to facilitate comprehension and educational enrichment to the preparation of a well-designed, practical approach.

LANGUAGE: ENGLISH

Authors: Martelli, Paolo;Segalés i Coma, Joaquim;Torremorell, Montse;Canelli, Elena;Maes, Dominiek;Nathues, Heiko;Brockmeier, Susan;Gottschalk, Marcelo;Aragón Fernández, Virginia
Release date: 2019
ISBN: 978-84-17225-86-5
Pages: 144
Binding: Hard cover
Dimensions: 17 x 24

1. Porcine respiratory disease complex: A combination of factors

2. Porcine reproductive and respiratory syndrome virus

3. Swine influenza virus

4. Aujeszky’s disease virus

5. Porcine circovirus type 2

6. Mycoplasma hyopneumoniae

7. Mycoplasma hyorhinis

8. Bordetella bronchiseptica

9. Actinobacillus pleuropneumoniae

10. Haemophilus parasuis

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Paolo Martelli

Paolo Martelli graduated (DVM) in Veterinary Medicine (with Honours) from the University of Parma (Italy) in 1984. Veterinary practitioner for 4 years, he started his career as a researcher in 1992. In 1998, he became Associate Professor and since 2002 he is Full Professor of Internal Medicine (Veterinary Clinical Medicine) at the University of Parma, Department of Veterinary Sciences. Paolo Martelli was Head of the Department for 7 years (2002–2008) and Vice Rector of the University of Parma for 3 years. He is a founding member (2004) and Diplomate of the European College of Porcine Health Management (ECPHM). He was coordinator of the PhD course in Animal Health and Veterinary Science at the University of Parma. Currently, Paolo Martelli is President of the ECPHM (2016–2019). He was President of the International Symposium on Emerging and Re-emerging Pig Diseases (Rome, Italy, 2003) and the 6th European Symposium of Porcine Health Management (ESPHM) (Sorrento, Italy, 2014). He was chair of the Scientific Committee of the 24th International Pig Veterinary Society Congress (IPVS)/8th ESPHM (Dublin, 2016). He also acted as President of the Italian Pig Veterinary Society (1995–2001 and 2007–2013). He has in charge the teaching of Physical examination and Internal Medicine - Clinics of Large Animals. His research activity focuses on porcine health management (porcine reproductive and respiratory syndrome virus [PRRSV], porcine circovirus type 2 [PCV-2], Mycoplasma hyopneumoniae, Actinobacillus pleuropneumoniae) and clinical and experimental immunology (vaccinology). He has been invited as speaker in more than 400 national and international conferences.

Joaquim Segalés
Joaquim Segalés obtained his DVM from the Universitat Autònoma de Barcelona (UAB, Spain) in 1991. After completing a 15-month research period at the University of Minnesota (USA), he defended his PhD at the UAB. He obtained his Dipl. European College of Veterinary Pathologists (ECVP) in 2000, and the Dipl. European College of Porcine Health Management (ECPHM) in 2004. Dr. Segalés was a founding member of the ECPHM and President of this College between 2013 and 2016. He is Associate Professor at the Veterinary School of the UAB (Department of Animal Health and Anatomy). He is also a researcher of the Centre de Recerca en Sanitat Animal (CReSA, Spain) and was its Director during the period 2012–2017. He also serves as a diagnostician at the Department of Pathology of the School of Veterinary Medicine of the UAB since 1996 where he was the responsible for the pathological diagnostic activity in swine for the period 1996–2012. Dr. Segalés has been involved in research of swine diseases since 1993, mainly infectious diseases (including infections caused by porcine reproductive and respiratory syndrome virus [PRRSV], Aujeszky’s disease virus, porcine circovirus type 2 [PCV-2], swine hepatitis E virus, swine Torque teno sus viruses [TTSuV], Actinobacillus pleuropneumoniae, Haemophilus parasuis and Mycoplasma hyopneumoniae). He has co-authored more than 250 articles in international peer-reviewed journals, and has recently started working on MERS (Middle East Respiratory Syndrome)-coronavirus infection animal models.

Montserrat Torremorell
Montserrat Torremorell is Associate Professor in the Department of Veterinary Population Medicine at the College of Veterinary Medicine of the University of Minnesota (USA). She obtained her DVM from the Universitat Autònoma de Barcelona (UAB, Spain) in 1994 and her PhD from the University of Minnesota in 1999. Dr. Torremorell joined the University of Minnesota as the Leman Chair in Swine Health and Productivity in May 2009. Prior to that, she was employed at Genus PIC, the largest swine breeding company in the world, in a range of roles related to health assurance and health research. Dr. Torremorell led the efforts in porcine reproductive and respiratory syndrome virus (PRRSV) elimination where PIC USA was able to move from 12 % to 100 % PRRSV-negative status in 5 years. She also participated in the National PRRSV Elimination program in Chile and more recently has worked in the control of other diseases such as swine influenza. Dr. Torremorell has an extensive background in swine health, research, and production systems, including health improvement strategies, disease eradication, diagnostics, biosecurity programs, and health genomics. She currently conducts research in influenza transmission and control to understand influenza dynamics in swine farms. She also researches biosecurity technologies with applicability to prevent and mitigate airborne infections in pigs. She teaches Veterinary Medicine to both DVM and graduate students and is passionate about helping producers and veterinarians to apply science to control diseases. She is also the director of the Swine Disease Eradication Center at the College of Veterinary Medicine of the University of Minnesota. Dr. Torremorell is the author of more than 70 peer-reviewed journal articles and more than 200 abstracts and articles in conference proceedings. She was awarded with the Allen D. Leman Science in Practice Award from the University of Minnesota in 2003 for her work on PRRS elimination. Her research interests include infectious diseases of swine focusing on influenza, PRRS and Haemophilus parasuis, and other swine diseases of economic significance as well research on biosecurity approaches to mitigate pathogen transmission.

Elena Canelli
Elena Canelli graduated (DVM) from the University of Parma (Italy) in 2006, and obtained a Specialist degree in Animal Health and Livestock Productions from the same university in 2009. In 2015, she obtained the PhD in Biotechnology applied to Veterinary Sciences from the University of Milan, discussing a thesis on the development of new diagnostic protocols to be applied to the study of avian rotaviruses. She also holds a second-level master’s degree in Molecular Virology in 2016 from the Faculty of Medicine and Pharmacology at La Sapienza University (Rome, Italy). In 2015, she started her residency program of the European College of Porcine Health Management (ECPHM) at the Department of Veterinary Sciences of the University of Parma. She has been working from 2006 at the Specialized Virology Laboratory of the Istituto Zooprofilattico Sperimentale della Lombardia e dell’Emilia Romagna (IZSLER, Brescia, Italy), focusing in particular on laboratory diagnostics. In 2010, she moved to the Virology Laboratory of the Istituto Zooprofilattico Sperimentale delle Regioni Lazio e Toscana (IZSLT, Rome), where she was concerned on molecular virology. She came back to the Specialized Virology Laboratory of the IZSLER from 2011 to 2014, continuing to work on virology, and also adding to her experience the electron microscopy expertise; she was also involved in different National and European research projects. Nowadays, she works at the University of Parma, Department of Veterinary Sciences, with a post-doctoral fellowship. She also works in the sanitary technical service, for swine farms, of an Italian feed company. Her professional activity focuses on virology, and particularly on viral diseases of livestock, laboratory diagnosis of viral infection, and molecular virology. Her current research concerns primarily swine immunity and vaccinology, and porcine health management. She is the author and co-author of several publications about virology on peer-reviewed journals, congress proceedings and textbooks.

Dominiek Maes
Dominiek Maes is Full Professor and Head of the Unit of Porcine Health Management at the Faculty of Veterinary Medicine of Ghent University (Belgium). He is a specialist of the European College of Porcine Health Management (ECPHM). His main research areas include respiratory disease, sow reproduction and production, Salmonella in pigs and antimicrobial use and resistance. The research group has performed lots of studies on Mycoplasma hyopneumoniae and has focused mainly on the pathogenesis and transmission of the pathogen, differences between mycoplasma strains, interaction of the pathogen with the animal host, antimicrobial treatment and resistance of M. hyopneumoniae field strains, and control measures, with emphasis on vaccination. He is Chair of the porcine section of the International Research Programme on Comparative Mycoplasmology (IRPCM), Standing Committee of the International Organization of Mycoplasmology (IOM). He has published over 260 papers in international peer-reviewed journals, from which over 50 on swine mycoplasmas. He has supervised 30 completed PhDs, and made more than 260 contributions to national and international conferences. He is Past President of the International Pig Veterinary Society Congress (IPVS) Belgian branch, the ECPHM, the European Board of Veterinary Specialisation (EBVS) and Past Director of the Institute for Continuing Professional Development at the Faculty of Veterinary Medicine of Ghent University. He is currently Chair of the Committee for Internationalization in the same faculty, section editor of Livestock Science, and editor-in-chief of the journal Porcine Health Management.

Heiko Nathues
Prof. Dr. med. vet. Heiko Nathues graduated from the University of Veterinary Medicine in Hannover (Germany) in 2004. He spent some month in a specialised pig and poultry practice in Northern Germany. From late 2004 until 2011 he was employed at the Field Station for Epidemiology of the University of Veterinary Medicine Hannover (Bakum, Germany), where he also obtained his Dr. med. vet. in 2007 and his PhD in 2011. The latter one was assigned with the “Konrad Boegel Young Talent Award for veterinary epidemiology and veterinary public health”. During his time in Bakum, he built up from the scratch a laboratory for molecular biology, serology and genetic engineering. Awarded with a Marie Curie Intra-European Fellowship, he joined the Veterinary Epidemiology, Economics and Public Health Group of the Royal Veterinary College (London, UK), from 2011 to 2013. He was involved in the development of within-herd transmission models for pig diseases and contributed to various research projects dedicated to porcine health management. He also obtained a Postgraduate Certificate in Veterinary Education. In 2013, he finalized his habilitation and received the venia legendi for “Pig diseases and population medicine” from the University of Veterinary Medicine Hannover. Since then, he is Professor at the Vetsuisse Faculty of the University of Bern (Switzerland), where he is heading the clinic for swine. Prof. Nathues is Diplomate of the European College of Porcine Health Management (ECPHM) and currently the Vice-President of the ECPHM. He is also Honorary Professor at the Jiangsu Academy of Agricultural Sciences (Nanjing, China). His primary areas of interest include diagnosis, epidemiology and control of porcine virus and mycoplasma diseases. His current research is focused on modelling diseases in pig herds, the improvement of diagnostic methods and the determination of the efficacy of methods to control the disease.

Susan Brockmeier
Susan Brockmeier received her DVM from the University of Missouri (Columbia, Missouri, USA), and a PhD in Veterinary Microbiology from Iowa State University (Ames, Iowa, USA). She is currently a Research Veterinary Medical Officer with the United States Department of Agriculture (USDA), Agricultural Research Service (ARS), at the National Animal Disease Center (Ames, Iowa, USA), where she has conducted swine infectious disease research for the past 25 years. Dr. Brockmeier has extensive experience working on polymicrobial infections and her work is centered around how bacterial pathogens establish infection and cause disease alone and in combination with other common viral and bacterial respiratory pathogens to produce the swine respiratory disease complex (PRDC). The disease models she has developed have been used to analyze pathogenesis, transmission, innate and adaptive immune responses, biotherapeutic interventions, and vaccine efficacy.

Marcelo Gottschalk
Marcelo Gottschalk received his DVM from the Faculty of Veterinary Medicine of the University of Buenos Aires (Argentina). He moved to Canada in 1987 where he completed a PhD at the University of Montreal. Since 2001, he is Full Professor at the Faculty of Veterinary Medicine of the University of Montreal, where he is the Director of the reference laboratory for the diagnosis of Actinobacillus pleuropneumoniae (App, aetiological agent of swine pleuropneumonia). He is also the Director of the international reference laboratory for Streptococcus suis. He founded the Swine Infectious Diseases Research Center at the Quebec province (Canada) and he was also the Director of the Research Group of Swine Infectious Diseases at the University of Montreal. He received the Degree of Doctor Honoris Causa from Ghent University (Belgium) in 2018. He has published more than 300 papers in international peer-reviewed journals and more than 150 papers in professional journals. He is also the author of two chapters of the reference book Diseases of Swine (Actinobacillosis and Streptococcus). He has been invited as speaker in more than 200 occasions from more than 35 countries by different universities, research centers, associations of swine practitioners, associations of swine producers and pharmaceutical companies. He has participated in more than 400 studies presented in different international meetings. His research is highly focused on App and S. suis.

Virginia Aragón
Virginia Aragón completed her PhD at the University of Navarra (Pamplona, Spain) working with virulent strains of Brucella, mainly B. melitensis and B. abortus. Her work provided her with the opportunity to continue her scientific career as postdoctoral fellow at three different universities in the USA. Dr. Aragón joined the Centre de Recerca en Sanitat Animal (CReSA, Spain) in 2003 and established herself as a leading scientist in the research line of respiratory bacterial infections of swine. Dr. Aragón has been involved in the genomic and functional characterization of the swine pathogen Haemophilus parasuis, with especial research interest in unravelling the molecular mechanisms and components responsible for H. parasuis pathogenesis. Currently, her research focus extends to understand the role of the nasal microbiota in controlling respiratory disease in swine. Her scientific achievements are published in peer-reviewed international journals in the areas of Microbiology and Veterinary Medicine and are also divulged to clinicians and producers in technical talks. Her research on H. parasuis has produced articles in international journals, one book chapter in the book Diseases of Swine, several doctoral thesis, divulgative publications and several communications in national and international congresses. She has been the principal investigator in five national projects on H. parasuis and nasal microbiota, and has collaborated in other projects since she joined CReSA. Dr. Aragón also participates in educational programs, teaching for Master students and supervising high schoolers through the Argó program (Autonomous University of Barcelona, UAB, Spain). In the last 5 years, she has participated in six research projects, has published 24 peer-reviewed articles (including one review), an invited editorial, one book chapter in Diseases of Swine, and she has supervised three PhD thesis and eight Master thesis.

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